Effects were analysed with linear mixed model analysis. Also, the number of drugs in use were measured. Complaints were defined as number of complaints independent of severity and number of complaints with impact on daily life (VAS-score ≥ 5 and influence on daily life on 5-point Likert scale: moderate-severe). Main outcome measures: Health-related quality of life (HR-QoL) was measured with EQ-5D-5L (utility) and EQ-VAS. 629 persons aged 70 years and over using seven or more chronic drugs were randomly assigned to usual care (n = 314 control group) or to receive a CMR (n = 315 intervention group) and were measured after 3 and 6 months. Setting and method: The DREAMeR study was a randomized controlled trial performed in 35 community pharmacies located throughout the Netherlands. Therefore, the objective of this study is to investigate the effects of a CMR, focused on personal goals, on quality of life and health-related complaints in older patients with polypharmacy. To improve quality of life a CMR could be more focused on health-related complaints and wishes of older persons. There is little evidence for effects on clinical outcomes. Bouvy 1,2 1SIR Institute for Pharmacy Practice and Policy, Leiden, 2Division of Pharmacoepidemiology & Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht, 3Department of Public Health and Primary care, 4Department of Gerontology and Geriatrics, Leiden University Medical Center (LUMC), Leiden, Netherlandsīackground and objective: A clinical medication review (CMR) can reduce drug-related problems (DRPs). CP-PC001: Effects of drug use reconsidered in the elderly using goal attainment scales during medication review: DREAMeR results of a randomized controlled trial S.
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